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Ingredient Summary
Resveratrol and Quercetin are naturally occuring
polyphenolic antioxidants found in the skin and seeds
of grapes, red wine and other food products. In
research studies, these compounds have been
examined for their angiogenesis inhibiting
characteristics and have been found to inhibit the
proliferation and migration of bovine aorta endothelial
cells as well as inhibit blood vessel tube formation in a
concentration dependent fashion.1
Vitamin E (Succinate) is a naturally occurring, fat
soluble antioxidant essential for human growth and
survival. In research studies, vitamin E (Succinate) has
been shown to inhibit the gene expression of a group
of growth factors strongly involved in the angiogenesis
process, VEGF.2
Bromelain is a naturally occuring mixture of sulfurcontaining
proteases from the stem of the pineapple
plant, Ananas comosus. In research studies, it has
been shown to interfere with the growth of abnormal
cells, inhibit platelet aggregation, and decrease the
spread of abnormal cells.3
Curcumin is the yellow pigment and active
component of tumeric, Curcuma longa. It is a potent
antioxidant as well as inhibitor of both COX and LOX
pathways. In research studies, curcumin has shown
to promote cell cycle arrest, induce apoptosis, and
inhibit angiogenesis.3
Baicalin is a natural flavinoid found in the naturally
occurring herb Scutellaria baicalensis Georgi,
commonly known as Baikal skullcap. In research
studies, baicalin has been shown to inhibit abnormal
cell proliferation through the induction of apoptosis
and cell cycle arrest.
Each Capsule Contains:
Resveratrol . . . . . . . . . . . . . . . . . . . . . . . . . . . 300 mg
Bromelain . . . . . . . . . . . . . . . . . . . . . . . . . . . . 125 mg
Curcumin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 125 mg
Baikal Skullcap . . . . . . . . . . . . . . . . . . . . . . . . . 50 mg
Quercetin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40 mg
Vitamin E (Succinate) . . . . . . . . . . . . . . . . . . . . . . 30 IU
Other Ingredients: Gelatin capsule, maltodextrin
Form: 60 Capsule Bottle Dietary Supplement
Suggested Intake: Take 1 - 2 capsules daily or as
directed by a health care professional.
Caution: Not intended for use by pregnant or
lactating women. If you are recovering from a recent
surgery, or have a heart or circulatory condition, seek
the advice of a health care professional before using.
References
1. Koichi I, Toshiro O, Yukiaki K, Kazuhiko K.
Resveratrol and quercetin inhibit angiogensis in vitro.
Cancer Letters, 2001; 171:11-16.
2. Malafa MP, Neitzel LT. Vitamin E succinate
promotes breast cancer tumor dormancy. J Surg
Res, Sept 2000; 93(1):163-70.
3. Wallace JM. Nutritional and botanical modulation
of the inflammatory cascade-eicosanoids,
cyclooxygenases, and lipoxygenases-as an adjunct in
cancer therapy.
4. Ikezoe T, Chen SS, Heber D, Taguchi H, Koeffler
HP. Baicalin is a major component of PC-SPEC which
inhibits the proliferation of human cancer cells via
apoptosis and cell cycle arrest.
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